On 13 March 2020 Ghana confirmed two cases which summed up to four cases in the country.
On 14 March 2020 Ghana confirmed two cases which summed up to six cases in the country.
On 15 March 2020, four new cases were confirmed in a live telecast by the Ministry of Health and Minister of Information. Traveling to Ghana had been strongly discouraged until further notice and non-admittance of travellers from countries where at least 200 cases of COVID-19 were recorded was declared; this restriction did not apply to Ghanaian citizens and people with resident permits. A web page was also created to provide official updates and information.
On 15 March 2020 at 10 pm, PresidentNana Akufo-Addo banned all public gatherings including conferences, workshops, funerals, festivals, political rallies, church activities and other related events to reduce the spread of COVID-19 at a press briefing on the state of COVID-19. Basic schools, senior high schools and universities, both public and private, have also been closed. Only BECE and WASSCE candidates are permitted to remain in school under social distancing protocols.
On 17 March 2020, the Minister of Finance, Ken Ofori-Atta, declared in Parliament that the $100 million announced by President Akufo-Addo to fight coronavirus is not ready. This revelation by the Minister did not go down well with many Ghanaians slamming the president for not being sincere and honest in such a precarious situation. Also on this day, Ghana confirmed another case which sums up to seven cases recorded in the Greater Accra Region.
On 18 March 2020, Ghana records two cases which sums up to nine cases . These were confirmed by NMIMR, both Ghanaians returning from the United Kingdom and the United Arab Emirates. On the same day, three Ghanaians in Europe died from the disease.
On 19 March 2020, KCCR confirmed two new cases in Kumasi, Ashanti Region, bringing the number of confirmed cases in the country to 11. Passport services were also suspended on this date.
On 20 March 2020, Ghana records five new cases were confirmed in the Greater Accra Region, raising total confirmed cases to 16.
On 21 March 2020, Ghana confirms three new cases which sums up to 19 patients. At 9 pm, Nana Akuffo Addo addressed the nation with Ghana's first death case from Kumasi.Two new cases were later confirmed making total of twenty-one confirmed in Ghana.
On 22 March 2020, three cases were confirmed in the country hence summing up to 24 cases.
On 23 March 2020, three cases were recorded which summed up to 27 cases. The Local Government Minister announced the disinfection of 137 markets in the Greater Accra Region. On that same day, all beaches were closed to help contain the spread of the pandemic. All of the county's borders were closed for a fortnight from midnight of Sunday the 22nd of March 2020.
On 24 March 2020 the Minister of Health announced 25 new confirmed cases and one new death case, hence totaling 52 COVID-19 patients and two deaths.
On 26 March 2020, 64 new cases were recorded which leads to a sum of 132 cases in Ghana. On the same day, a letter written and signed by the Director General of the Ghana Health Service recalled all staff on study leave into active service. This was to help accommodate the workload on health centres.
On 27 March 2020, Ghana confirmed three cases with a total of 137 cases. The first case recorded in the Upper West Region was made known at press briefing in Wa. The President addressed the nation at 11pm with an announcement, that placed some key cities in Accra and Kumasi under a partial lock down, effective from Monday 30 March 2020. Some services such as Members of the Executive, Legislature and the Judiciary; Production, distribution and marketing of food, beverages, pharmaceuticals, medicine, paper and plastic packages were exempted from the restrictions.
On 28 March 2020 the total number of confirmed cases rose to 141 and the total number of deaths stood at five. A special life insurance cover for the professionals at the frontline dealing with the pandemic,was announced by the Ghana Health Ministry. The workers were insured under Group Life cover,with an assured sum of GHS 350,000 on each life.
On 29 March 2020 the government of Ghana set up a quarantine centre at the Northern Regional capital, Tamale after the confirmation of 10 new cases of COVID-19 recorded in that part of the country bringing the number of case count for COVID-19 to 152.
On 30 March 2020 the partial lock down of Accra and Kumasi took effect No new cases were recorded on this day.
On 31st March 2020,nine new cases were confirmed bringing the number to 161. The new cases were all in Accra. Three of the infected persons had returned from journeys to Germany, France and Hungary. 
On 1 April 2020, the number of confirmed cases reached 195 with more security checkpoints and roadblocks set up in Accra. There was a bit of heavy vehicular traffic at many of the barriers and most commercial vehicles were not allowed to cross the Tema motorway.
On 2 April 2020,nine new cases are confirmed, making the total 204. All new cases are from the Greater Accra Region. The nine cases consist of four who have no contact with confirmed cases nor a travel history,four who are contacts of confirmed cases and one traveling to Ghana from Benin within the last 14 days.Two cases are in critical condition.
^"Coronavirus cases in Ghana jump to 52". Citinewsroom - Comprehensive News in Ghana, Current Affairs, Business News , Headlines, Ghana Sports, Entertainment, Politics. 24 March 2020. Retrieved 24 March 2020.